The ministry said on Twitter that there had been a confirmed Ebola case in the central Mubende district, a 24-year-old man who showed symptoms and later died.
The WHO's Africa office said in a statement that the case was of the relatively rare Sudan strain after Ugandan health authorities investigated six suspicious deaths in the district this month.
"There are currently eight suspected cases who are receiving care in a health facility," WHO Africa said, adding it was helping Uganda's health authorities with their investigation and deploying staff to the affected area.
Marburg Virus
A child who contracted the highly infectious Ebola-like Marburg virus in Ghana has died, a World Health Organization official said on Tuesday.
The death brings the total number of fatalities in the country to two since Ghana registered its first-ever outbreak of the disease last month.
The outbreak is only the second in West Africa. The first-ever case of the virus in the region was detected last year in Guinea.
The virus is transmitted to people from fruit bats and spreads among humans through direct contact with bodily fluids, surfaces and materials, the WHO said.
The dead child, whose gender or age was not disclosed, was one of two new cases reported last week by WHO.
"Last week, I mentioned the two additional cases. One is the wife of the index case, and the other one is the child of the index case, and the child unfortunately died, but the wife is still alive and improving," WHO doctor Ibrahima Soce Fall told reporters.
The Ghanaian health ministry has only reported three confirmed cases, and further testing remains to be done on a fourth suspected case, Soce Fall said.
The first two cases, in southern Ghana's Ashanti region, both had symptoms including diarrhoea, fever, nausea and vomiting before dying in hospital, the WHO said previously.
But one of those two cases was later declared a false-positive. - Reuters.